Vibration Exercise for Crohn's to Observe Response

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Background: Crohn's disease (CD) is a long-term inflammatory condition of the digestive system. People with CD often have unpredictable and debilitating symptoms, including abdominal pain, diarrhoea and fatigue. In addition, they require long-term treatment with frequent negative effects and often need surgery and hospitalisations. Therefore, people with CD report a lower health-related quality of life (HRQOL) compared with other people. Doctors are constantly trying to find new treatments to improve HRQOL and control symptoms and whole body vibration exercise could be a potential treatment. Exercise might be a simple, safe, and low-cost intervention for improving HRQOL in people with CD. This is because it has the potential to improve several aspects of physical, mental and social well-being simultaneously. Adults with CD have been shown to be less active than the general population and do not meet the recommended daily physical activity guidelines. One barrier to exercise is lack of time, however whole-body vibration exercise (where you stand and squat on a vibrating plate) can be done over a much shorter duration and at a lower intensity to gain potentially similar or at times greater benefits. More research is needed to understand the effects, both positive and negative of vibration exercise in people with CD. Aim: This study begins to understand whether undertaking a supervised 6-week vibration exercise programme for adults with mild to moderately active Crohn's disease improves HRQoL and other symptoms such as fatigue.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• Aged over 18-65 years old

• Clinical diagnosis of CD for at least 4 weeks before randomization

‣ Mild to moderate active CD (150-220 CDAI)

⁃ Stable medication for at least 4 weeks before randomization

⁃ Able to provide written consent, complete the study questionnaires and travel to the research centre for study assessment visits and exercise sessions

⁃ Be doing less than 60 minutes of purposeful exercise per week

Locations
Other Locations
United Kingdom
University of Hertfordshire
RECRUITING
Hatfield
Contact Information
Primary
Lindsay Bottoms
l.bottoms@herts.ac.uk
+441707285685
Time Frame
Start Date: 2025-03-31
Estimated Completion Date: 2028-01-01
Participants
Target number of participants: 168
Treatments
Experimental: Vibration Exercise
No_intervention: Control
Related Therapeutic Areas
Sponsors
Collaborators: Anglia Ruskin University, University of Central Lancashire
Leads: University of Hertfordshire

This content was sourced from clinicaltrials.gov